SARSCoV2

Prior infection and vaccination protect against severe consequences of SARS-CoV-2 infection Omicron

Prior infection and vaccination protect against severe consequences of SARS-CoV-2 infection Omicron

A new study published in The Journal of Infectious Diseases reports that prior infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and booster vaccination protect against intensive care unit (ICU) admission and mortality following infection with the SARS variant -CoV-2 Omicron. However, the scope of this protection is reduced against the Omicron variant compared …

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Study: Recombination-aware phylogenetic analysis sheds light on the evolutionary origin of SARS-CoV-2. Image Credit: NicoElNino/Shutterstock

Scientists study the evolutionary origin of SARS-CoV-2 using recombination-sensitive phylogenetic analysis

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe acute respiratory syndrome coronavirus (SARS-CoV) belong to the subgenus Sarbecovirus, which has a genomic length of approximately 30,000 base pairs. These viruses encode four structural proteins, namely spike (S), envelope (E), membrane (M), and nucleocapsid (N). Study: Recombination-aware phylogenetic analysis sheds light on the evolutionary origin …

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Study: Lineage frequency time series reveal elevated levels of genetic drift in SARS-CoV-2 transmission in England. Image Credit: creativeneko/Shutterstock

Strength of SARS-CoV-2 genetic drift across time and spatial scales in England

In a recent study published on bioRxiv* preprint server, researchers developed and validated an approach for the joint inference of measurement noise and genetic drift by analyzing lineage frequency time series data. Study: Lineage frequency time series reveal high levels of genetic drift in SARS-CoV-2 transmission in England. Image Credit: creativeneko/Shutterstock Background Random genetic drift …

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