RNA

Prior infection and vaccination protect against severe consequences of SARS-CoV-2 infection Omicron

Prior infection and vaccination protect against severe consequences of SARS-CoV-2 infection Omicron

A new study published in The Journal of Infectious Diseases reports that prior infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and booster vaccination protect against intensive care unit (ICU) admission and mortality following infection with the SARS variant -CoV-2 Omicron. However, the scope of this protection is reduced against the Omicron variant compared …

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Study: Inflammatory bone marrow signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes. Image Credit: Nemes Laszlo/Shutterstock

Genetic subtypes of pediatric acute myeloid leukemia with poor outcomes show increased signaling of inflammatory cytokines

In a recent study published in Nature Communicationresearchers used ribonucleic acid (RNA) sequence data to understand the association between inflammatory cytokines and poor outcomes in pediatric acute myeloid leukemia (pAML). Study: Bone marrow inflammatory signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes. Image Credit: Nemes Laszlo/Shutterstock Background Pediatric acute myeloid leukemia is …

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RNA targeting strategy for the treatment of genetic causes of dementia

RNA targeting strategy for the treatment of genetic causes of dementia

UF Scripps Biomedical Research scientists have developed a potential drug for a major cause of ALS and dementia that works by removing disease-causing RNA segments. The compound restored the health of neurons in the lab and saved mice with disease. The potential drug is described this week in the scientific journal Proceedings of the National …

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Genetic cause of ALS and dementia repaired by RNA targeting strategy developed at UF Scripps

Genetic cause of ALS and dementia repaired by RNA targeting strategy developed at UF Scripps

UF Scripps Biomedical Research scientists have developed a potential drug for a major cause of ALS and dementia that works by removing disease-causing RNA segments. The compound restored the health of neurons in the lab and saved mice with disease. The potential drug is described this week in the scientific journal Proceedings of the National …

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