This is how an Alzheimer's gene ravages the brain

This is how an Alzheimer’s gene ravages the brain

A neuron (green) from a person with Alzheimer’s disease includes an unusual protein complex (pink) surrounding the nucleus (yellow).Credit: Thomas Deerinck, NCMIR/SPL No genetic variant is a greater risk factor for Alzheimer’s disease than a variant called APOE4. But exactly how the gene stimulates brain damage is a mystery. A study1 has now bound APOE4 …

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