Protein

Study: Genome charaterization based on the Spike-614 and NS8-84 loci of SARS-CoV-2 reveals two major onsets of the COVID-19 pandemic. Image Credit: peterschreiber.media/Shutterstock

New study describes two possible major outbreaks of the COVID-19 pandemic

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Chinese scientists have analyzed millions of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes and identified two main genetic drivers of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Study: Genome characterization based on SARS-CoV-2 loci Spike-614 and NS8-84 reveals two major outbreaks of the COVID-19 pandemic. Image Credit: peterschreiber.media/Shutterstock The study is currently available on …

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The protein mutation that causes Parkinson's disease could prevent another neurodegenerative disease

The protein mutation that causes Parkinson’s disease could prevent another neurodegenerative disease

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image: Amanda Woerman is an assistant professor of biology at UMass Amherst. see After Credit: UMass Amherst A scientist at the University of Massachusetts Amherst has discovered that a mutation in the misfolded protein that causes Parkinson’s disease offers protection against another deadly neurodegenerative disease – multiple system atrophy (MSA), which is caused by the …

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Study: Inflammatory bone marrow signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes. Image Credit: Nemes Laszlo/Shutterstock

Genetic subtypes of pediatric acute myeloid leukemia with poor outcomes show increased signaling of inflammatory cytokines

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In a recent study published in Nature Communicationresearchers used ribonucleic acid (RNA) sequence data to understand the association between inflammatory cytokines and poor outcomes in pediatric acute myeloid leukemia (pAML). Study: Bone marrow inflammatory signaling in pediatric acute myeloid leukemia distinguishes patients with poor outcomes. Image Credit: Nemes Laszlo/Shutterstock Background Pediatric acute myeloid leukemia is …

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Researchers find repeated genetic duplications and genetic diversification in protein kinase R in mouse-eared bats

Researchers find repeated genetic duplications and genetic diversification in protein kinase R in mouse-eared bats

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1) for each codon (X axis). Red bars indicate sites with a BEB > 0.95. The numbers in parentheses represent the total number of species analyzed. Viral antagonists: herpes virus US11, influenza A virus (IAV) NS1A, poxvirus E3 and K3 (green striped boxes), hepatitis C virus (HCV) NS5A and human immunodeficiency virus Tat, which interact …

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Discovery of a new function of the CRISPR gene scissors: the protein scissors activate the defense function

Discovery of a new function of the CRISPR gene scissors: the protein scissors activate the defense function

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Uncropped and unedited version of all gels used in this study. The red box indicates the portion of the gel that is shown in the indicated figures. Credit: Nature (2022). DOI: 10.1038/s41586-022-05571-7 For several years, the CRISPR/Cas9 gene scissors have caused a stir in science and medicine. This new molecular biology tool has its origins …

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Study: Recombination-aware phylogenetic analysis sheds light on the evolutionary origin of SARS-CoV-2. Image Credit: NicoElNino/Shutterstock

Scientists study the evolutionary origin of SARS-CoV-2 using recombination-sensitive phylogenetic analysis

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe acute respiratory syndrome coronavirus (SARS-CoV) belong to the subgenus Sarbecovirus, which has a genomic length of approximately 30,000 base pairs. These viruses encode four structural proteins, namely spike (S), envelope (E), membrane (M), and nucleocapsid (N). Study: Recombination-aware phylogenetic analysis sheds light on the evolutionary origin …

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Chinese scientists increase corn protein as food by successfully cloning a mutant gene in wild corn

Chinese scientists increase corn protein as food by successfully cloning a mutant gene in wild corn

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Human ancestors began domesticating maize 9,000 years ago and gradually transformed the weed-like wild maize teosinte into what we have today. Source: The Paper A couple of scientists in Shanghai have cloned a mutant gene in wild corn after 10 years of effort, dramatically increasing the protein content of corn. This study is not only …

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Researchers provide new insight into the frustrating process that makes HIV stealth

Researchers provide new insight into the frustrating process that makes HIV stealth

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An immune response that likely evolved to help fight infections appears to be the mechanism that pushes the human immunodeficiency virus (HIV) into a latent state, hiding in cells to burst out again, Duke Health researchers report. . Publication on November 14 in the journal Natural microbiologythe research team provides new insights into the vexing …

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