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Researchers determine genetic variants offering protection during the Black Death

Researchers determine genetic variants offering protection during the Black Death

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Infectious diseases are among the strongest selective pressures in human evolution, selecting genetic variants that increase resistance to infection. In the face of a pandemic, disease resistance undergoes strong positive selection which probably affects the genetic make-up of the population thereafter. The Black Death, also known as the bubonic plague, remains the most devastating pandemic …

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Genetic variants that offered protection during the Black Death are also associated with current autoimmune disorders – Neuroscience News

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Summary: People with selected variants of the ERAP2 and TICAM2 genes were 40% more likely to survive the Black Death, the researchers found. However, in modern humans, those with the ERAP2 gene are more likely to suffer from autoimmune diseases such as Crohn’s disease. Source: University of Illinois Infectious diseases are among the strongest selective …

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Roswell Park team, Genome Protection Inc., discovers how retrotransposons fuel drug resistance in tumors

Roswell Park team, Genome Protection Inc., discovers how retrotransposons fuel drug resistance in tumors

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Antiviral drugs can suppress tumor adaptation to treatment and significantly prolong progression-free survival BUFFALO, NY – Researchers at the Roswell Park Comprehensive Cancer Center, working in collaboration with Genome Protection, Inc. and the Children’s Cancer Institute in Sydney, Australia, have discovered a new way in which highly repetitive genetic components belonging to the LINE-family 1 …

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Wildlife conference bolsters protection for sharks and turtles

Wildlife conference bolsters protection for sharks and turtles

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PANAMA CITY (AP) — An international wildlife conference has moved to enact some of the most important protections for shark species targeted in the fin trade and dozens of turtles, lizards and frogs whose numbers are being decimated by the pet trade. The Convention on International Trade in Endangered Species of Wild Fauna and Flora, …

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Safety in space: synthetic hibernation could provide protection against cosmic radiation

Safety in space: synthetic hibernation could provide protection against cosmic radiation

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The SIS18 accelerator at GSI/FAIR in Darmstadt can be used to simulate cosmic radiation. Credit: J. Hosan, GSI/FAIR This is another glimpse of the future: astronauts could be put into artificial hibernation and in this state be better protected from cosmic radiation. Currently, there are already promising approaches to address these considerations. An international research …

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