Diabetic status alters the impact of a single nucleotide polymorphism associated with NAFLD
Non-alcoholic steatohepatitis (NASH) is a common disease that affects nearly one billion people worldwide. Early identification of susceptible individuals is therefore essential for precision hepatology. In this issue, Takebe et al. to use human liver organoids and perform mass population-based phenotypic analysis under insulin-insensitive conditions to study the main genetic factors of NASH. In the …
