Parkinsons

The protein mutation that causes Parkinson's disease could prevent another neurodegenerative disease

The protein mutation that causes Parkinson’s disease could prevent another neurodegenerative disease

image: Amanda Woerman is an assistant professor of biology at UMass Amherst. see After Credit: UMass Amherst A scientist at the University of Massachusetts Amherst has discovered that a mutation in the misfolded protein that causes Parkinson’s disease offers protection against another deadly neurodegenerative disease – multiple system atrophy (MSA), which is caused by the …

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Gut microbiome at center of Parkinson’s disease pathogenesis – Neuroscience News

Summary: In addition to previous research on the link between the gut-brain axis and Parkinson’s disease, researchers have found that the gut microbiome is involved in multiple pathways in the pathogenesis of Parkinson’s disease. Source: University of Alabama at Birmingham New research from the University of Alabama at Birmingham indicates that the gut microbiome is …

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New study puts the gut microbiome at the center of the pathogenesis of Parkinson's disease

New study puts the gut microbiome at the center of the pathogenesis of Parkinson’s disease

The study, using the relatively new field of metagenomics, demonstrated an imbalance in the gut microbiome of patients with Parkinson’s disease. Haydeh Payami, Ph.D.New research from the University of Alabama at Birmingham indicates that the gut microbiome is involved in multiple pathways in the pathogenesis of Parkinson’s disease. The results, published in Nature Communications, show …

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Repetitive genetic variations linked to Parkinson’s risk in a study | News about Parkinson’s disease today

According to a new study, variations in small repetitive DNA sequences called short tandem repeats (STRs) are associated with an altered risk of developing Parkinson’s disease. “We demonstrate for the first time that these complex repeat regions actually influence a person’s risk of disease and reduce understanding of all of the complex genetic factors that …

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How Parkinson’s disease progresses linked to elements of the “dark genome” | Parkinson’s disease news

Transposable elements, a common feature of the so-called “dark genome”, are associated with clinical differences in the progression of Parkinson’s disease in different people, according to a new study. “Our main finding is that the presence or absence of [transposable elements] changes the progression trajectory of [Parkinson’s]and we have provided supporting clinical, imaging and biochemical …

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Brain Scan AI Analysis

A new discovery could solve a mystery of Parkinson’s disease

The research could lead to new strategies for the treatment of Parkinson’s disease. A recent study reveals how Parkinson’s disease spreads throughout the brain. According to a recent study by scientists at Weill Cornell Medicine, aggregates of the protein alpha-synuclein spread through the brains of patients with Parkinson’s disease through a process of ejection of …

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New approach may help design shorter, more powerful trials to evaluate drugs for Parkinson's disease

New approach may help design shorter, more powerful trials to evaluate drugs for Parkinson’s disease

Testing whether a new drug has an impact on the progression of Parkinson’s disease takes years, in part because the disease often progresses very slowly. Many patients with Parkinson’s disease experience no worsening of their symptoms during a typical clinical trial, even without treatment. Now Scripps Research scientists have developed a tool that analyzes genetic …

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