Is dopamine dysregulation responsible for schizophrenia?
Post-mortem genetic analysis of the brains of patients with schizophrenia suggests that dysfunction of dopamine receptors in the caudate nucleus may be the cause of the disorder. Researchers have identified a mechanism on the dopamine receptor, known as the autoreceptor, that regulates the amount of dopamine released by the presynaptic neuron. Impairment of this autoreceptor …
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