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Discovery paves way for development of new therapies for Chagas disease

Discovery paves way for development of new therapies for Chagas disease

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Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, affects some 8 million people worldwide. More than a third develop serious heart or digestive problems with an increased risk of death. The process that leads to this clinical condition is not completely understood. An article published in the journal Biomedicines describes a study by Brazilian …

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Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

Researchers develop 3D organoid model to advance understanding of gastroesophageal junction cancer

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Johns Hopkins Medicine researchers claim to have created a three-dimensional, lab-grown ‘organoid’ model derived from human tissue and designed to advance understanding of how early stages of cancer develop at the gastroesophageal junction (GEJ) – the point where the food pipe of the digestive system meets the stomach. A report on the results of the …

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Human evolution was not just a score, but how it was played: Research

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YEARS | Updated: November 27, 2022 01:11 IS North Carolina [US], Nov 27 (ANI): A group of human DNA sequences that appear to have evolved rapidly after our family line split from that of chimpanzees but before our split from Neanderthals has been discovered by a team of Duke scientists. These sequences are thought to …

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Researchers discover how phage resistance contributes to the emergence of dominant strains of Salmonella

Researchers discover how phage resistance contributes to the emergence of dominant strains of Salmonella

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Researchers from the Quadram Institute and the University of East Anglia have discovered how resistance has contributed to the emergence of dominant strains of Salmonella. In addition to antimicrobial resistance, bacteriophage resistance can give these insects a boost, at least in the short term. With the rise in antimicrobial resistance, the search for new ways …

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Researchers discover how phage resistance contributes to the emergence of dominant strains of Salmonella

Researchers discover how phage resistance contributes to the emergence of dominant strains of Salmonella

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Researchers from the Quadram Institute and the University of East Anglia have discovered how resistance has contributed to the emergence of dominant strains of Salmonella. In addition to antimicrobial resistance, bacteriophage resistance can give these insects a boost, at least in the short term. With the rise in antimicrobial resistance, the search for new ways …

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Genetics play a role in regulating the metabolism of essential polyunsaturated fatty acids

Genetics play a role in regulating the metabolism of essential polyunsaturated fatty acids

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Genetic background has an effect on the metabolism of essential polyunsaturated fatty acids, alpha-linolenic acid and linoleic acid, according to a recent study from the University of Eastern Finland. Supplementing the diet with camelina oil rich in alpha-linolenic acid, or with sunflower oil rich in linoleic acid modifies the concentrations of the metabolites of these …

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Study: Rare and common genetic determinants of metabolic individuality and their effects on human health. Image Credit: PopTika/Shutterstock

Metabolomic study of the genetic regulation of biochemical individuality

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In a recent study published in natural medicineresearchers systematically studied the genetic makeup of nearly 20,000 women and men in terms of >900 metabolites. Study: Rare and common genetic determinants of metabolic individuality and their effects on human health. Image Credit: PopTika/Shutterstock Metabolites circulating in the human body reflect human physiology and the chemical uniqueness …

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Whole Metagenome Analysis Helps Identify Depressive Gut Microbe

Whole Metagenome Analysis Helps Identify Depressive Gut Microbe

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In a three-year study, researchers from Skoltech, the RAS Vavilov Institute of General Genetics, Moscow Mental Health Clinic No. 1 named after NA Alexeev, and the Federal Medical Research Center of Psychiatry and Serbsky’s Narcology examined how gut microbes in patients with major depressive disorder are different from those in mentally healthy people. After analyzing …

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Study shows hereditary risk factors for appendix cancer

Study shows hereditary risk factors for appendix cancer

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One in 10 appendix cancer patients carry germline genetic variant associated with predisposition to cancer, study finds JAMA Oncology it is the first to show hereditary risk factors for this rare cancer. Appendix cancer affects about one or two people per million each year. Historically, appendicular cancer was thought not to be inherited, but its …

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