Biomarkers

Slowing down ALS with speech: Study uses IBM AI to create digital biomarkers

Slowing down ALS with speech: Study uses IBM AI to create digital biomarkers

The study‚Äč EverythingALS is working with clinical research stakeholders from IBM Research, Massachusetts Institute of Technology, and Harvard University in a longitudinal study focused on early disease detection based on patterns scored in audiovisual sessions. The study includes more than 800 participants diagnosed with amyotrophic lateral sclerosis (ALS), caregivers, those suspected of developing ALS due …

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Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028) - BMC Medicine

Identifying and Ranking Causative Biochemical Biomarkers of Breast Cancer: A Mendelian Randomization Study – BMC Medicine

Analysis plan Our prospective plan was to perform a variety of two-sample univariate MR (UVMR) analyzes to examine the associations of each of the UKB biochemical biomarkers with global, ER-positive and ER-negative breast cancer causation. Once our UVMR analyzes showed significant associations, we performed further multivariate MR (MVMR) analyzes to adjust for known risk factors …

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