biochemical

Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028) - BMC Medicine

Identifying and Ranking Causative Biochemical Biomarkers of Breast Cancer: A Mendelian Randomization Study – BMC Medicine

Analysis plan Our prospective plan was to perform a variety of two-sample univariate MR (UVMR) analyzes to examine the associations of each of the UKB biochemical biomarkers with global, ER-positive and ER-negative breast cancer causation. Once our UVMR analyzes showed significant associations, we performed further multivariate MR (MVMR) analyzes to adjust for known risk factors …

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Study: Rare and common genetic determinants of metabolic individuality and their effects on human health. Image Credit: PopTika/Shutterstock

Metabolomic study of the genetic regulation of biochemical individuality

In a recent study published in natural medicineresearchers systematically studied the genetic makeup of nearly 20,000 women and men in terms of >900 metabolites. Study: Rare and common genetic determinants of metabolic individuality and their effects on human health. Image Credit: PopTika/Shutterstock Metabolites circulating in the human body reflect human physiology and the chemical uniqueness …

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