Alzheimers

By Sharing Their Genetic Risks, Hemsworth and Jolie Raise Awareness About Testing, by Robert C. Green

By Sharing Their Genetic Risks, Hemsworth and Jolie Raise Awareness About Testing, by Robert C. Green

Robert C. Green Chicago Tribune When actor Chris Hemsworth, aka Thor, God of Thunder, agreed to host a National Geographic series about extending human lifespans, he didn’t expect to discover his own genetic risk. But that’s what happened when Hemsworth revealed on an episode of “Limitless” that he carries a common change in the APOE …

By Sharing Their Genetic Risks, Hemsworth and Jolie Raise Awareness About Testing, by Robert C. Green Read More »

Alzheimer's risk linked to genetic propensity for ADHD

Alzheimer’s risk linked to genetic propensity for ADHD

A genetic predisposition to attention-deficit/hyperactivity disorder (ADHD) has been linked to an increased risk of cognitive decline and Alzheimer’s disease in older adults, according to a new study from the University of Pittsburgh. The findings are the first to link the genetic risk of ADHD to age-related cognitive impairment. The hypothesis that ADHD might increase …

Alzheimer’s risk linked to genetic propensity for ADHD Read More »

Dementia: low levels of vitamin D linked to poor cognitive function

Dementia: low levels of vitamin D linked to poor cognitive function

Share on PinterestA new study has found that lower levels of vitamin D are associated with a higher risk of dementia in older people. Andriy Onufriyenko/Getty Images For the first time, a new study has explored vitamin D levels in the human brain and the potential effect on cognitive outcomes. Researchers have found that higher …

Dementia: low levels of vitamin D linked to poor cognitive function Read More »

A drug to prevent Alzheimer's?  Study to start enrolling young participants in the ultimate test

A drug to prevent Alzheimer’s? Study to start enrolling young participants in the ultimate test

article FILE – A woman holds a model of the human brain in her hands on June 1, 2019 in Cardiff, UK. (Photo by Matthew Horwood/Getty Images) Researchers are soon recruiting participants for a study aimed at preventing Alzheimer’s disease in people genetically destined to develop it at a young age. Depending on the result, …

A drug to prevent Alzheimer’s? Study to start enrolling young participants in the ultimate test Read More »

A drug to prevent Alzheimer's?  Study to start enrolling young participants in the ultimate test

A drug to prevent Alzheimer’s? Study to start enrolling young participants in the ultimate test

article FILE – A woman holds a model of the human brain in her hands on June 1, 2019 in Cardiff, UK. (Photo by Matthew Horwood/Getty Images) Researchers are soon recruiting participants for a study aimed at preventing Alzheimer’s disease in people genetically destined to develop it at a young age. Depending on the result, …

A drug to prevent Alzheimer’s? Study to start enrolling young participants in the ultimate test Read More »

Genetic risk of attention-deficit/hyperactivity disorder predicts cognitive decline and development of Alzheimer’s disease pathophysiology in older adults without cognitive impairment – Molecular Psychiatry

Faraone SV, Banaschewski T, Coghill D, Zheng Y, Biederman J, Bellgrove MA, et al. ADHD World Federation International Consensus Statement: 208 evidence-based conclusions about the disorder. Neurosci Biobehav Rev. 2021 https://www.sciencedirect.com/science/article/pii/S014976342100049X Caye A, Spadini AV, Karam RG, Grevet EH, Rovaris DL, Bau CHD, et al. Predictors of persistence of ADHD in adulthood: systematic review of …

Genetic risk of attention-deficit/hyperactivity disorder predicts cognitive decline and development of Alzheimer’s disease pathophysiology in older adults without cognitive impairment – Molecular Psychiatry Read More »

Promising trial targets genetic risk for Alzheimer's disease

Promising trial targets genetic risk for Alzheimer’s disease

In a bold attempt to halt the progression of some cases of Alzheimer’s disease, a group of researchers are trying something new: injecting a protective gene into patients’ brains. The trial only involved five patients with a particular genetic risk for Alzheimer’s disease. They received a very low dose of gene therapy – a safety …

Promising trial targets genetic risk for Alzheimer’s disease Read More »

Promising trial targets genetic risk for Alzheimer's disease

Promising trial targets genetic risk for Alzheimer’s disease

In a bold attempt to halt the progression of some cases of Alzheimer’s disease, a group of researchers are trying something new: injecting a protective gene into patients’ brains. The trial only involved five patients with a particular genetic risk for Alzheimer’s disease. They received a very low dose of gene therapy – a safety …

Promising trial targets genetic risk for Alzheimer’s disease Read More »

Experimental drug appears to slow progression of Alzheimer's disease in clinical trial, but raises safety concerns

Experimental drug appears to slow progression of Alzheimer’s disease in clinical trial, but raises safety concerns

(CNN) – The investigational drug lecanemab shows “potential” as a treatment for Alzheimer’s disease, according to new Phase 3 trial results, but the results raise safety concerns because of its association with certain events serious adverse reactions. Lecanemab has become one of the first experimental dementia drugs to appear to slow the progression of cognitive …

Experimental drug appears to slow progression of Alzheimer’s disease in clinical trial, but raises safety concerns Read More »

Tau and APOE

Why Alzheimer’s Disease Damages Parts of the Brain – New Genetic Clues

The red and orange areas on these heatmaps of the human brain show where the APOE gene is most active (two upper brain images) and where tau tangles are most concentrated (two lower brain images). APOE is the greatest genetic risk factor for Alzheimer’s disease, and tau tangles lead to brain damage in the disease. …

Why Alzheimer’s Disease Damages Parts of the Brain – New Genetic Clues Read More »