alters

Diabetic status alters the impact of a single nucleotide polymorphism associated with NAFLD

Diabetic status alters the impact of a single nucleotide polymorphism associated with NAFLD

Non-alcoholic steatohepatitis (NASH) is a common disease that affects nearly one billion people worldwide. Early identification of susceptible individuals is therefore essential for precision hepatology. In this issue, Takebe et al. to use human liver organoids and perform mass population-based phenotypic analysis under insulin-insensitive conditions to study the main genetic factors of NASH. In the …

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Key Alzheimer's gene alters the way cholesterol moves through the brain, study finds

Key Alzheimer’s gene alters the way cholesterol moves through the brain, study finds

A gene known to be the strongest risk factor for Alzheimer’s disease (AD) alters the way cholesterol moves through the brain, and as we age, this altered movement likely contributes to learning loss and memory, a team of researchers from the Icahn School of Medicine at Mount Sinai and the Massachusetts Institute of Technology (MIT) …

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